A need for exhaustive and standardized characterization of ion channels activity. The case of K(V)11.1

hERG, the pore-forming subunit of the rapid component of the delayed rectifier K(+) current, plays a key role in ventricular repolarization. Mutations in the KCNH2 gene encoding hERG are associated with several cardiac rhythmic disorders, mainly the Long QT syndrome (LQTS) characterized by prolonged...

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Detalles Bibliográficos
Autores principales: Alameh, Malak, Oliveira-Mendes, Barbara Ribeiro, Kyndt, Florence, Rivron, Jordan, Denjoy, Isabelle, Lesage, Florian, Schott, Jean-Jacques, De Waard, Michel, Loussouarn, Gildas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968853/
https://www.ncbi.nlm.nih.gov/pubmed/36860515
http://dx.doi.org/10.3389/fphys.2023.1132533

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