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Therapeutic targeting of HCMV-encoded chemokine receptor US28: Progress and challenges

The pervasive human cytomegalovirus (HCMV) causes significant morbidity in immunocompromised individuals. Treatment using the current standard-of-care (SOC) is limited by severe toxic adverse effects and anti-viral resistance development. Furthermore, they only affect HCMV in its lytic phase, meanin...

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Detalles Bibliográficos
Autores principales: Berg, Christian, Rosenkilde, Mette M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9968965/
https://www.ncbi.nlm.nih.gov/pubmed/36860859
http://dx.doi.org/10.3389/fimmu.2023.1135280