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IL-12α deficiency attenuates pressure overload-induced cardiac inflammation, hypertrophy, dysfunction, and heart failure progression

IL-12α plays an important role in modulating inflammatory response, fibroblast proliferation and angiogenesis through modulating macrophage polarization or T cell function, but its effect on cardiorespiratory fitness is not clear. Here, we studied the effect of IL-12α on cardiac inflammation, hypert...

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Detalles Bibliográficos
Autores principales:	Bhattarai, Umesh, He, Xiaochen, Xu, Rui, Liu, Xiaoguang, Pan, Lihong, Sun, Yuxiang, Chen, Jian-Xiong, Chen, Yingjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969090/ https://www.ncbi.nlm.nih.gov/pubmed/36860846 http://dx.doi.org/10.3389/fimmu.2023.1105664

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