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Factors influencing plasma concentration of voriconazole and voriconazole- N-oxide in younger adult and elderly patients
Background: Voriconazole (VCZ) metabolism is influenced by many factors. Identifying independent influencing factors helps optimize VCZ dosing regimens and maintain its trough concentration (C(0)) in the therapeutic window. Methods: We conducted a prospective study investigating independent factors...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969092/ https://www.ncbi.nlm.nih.gov/pubmed/36860301 http://dx.doi.org/10.3389/fphar.2023.1126580 |