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CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway

Hydrogen sulfide (H(2)S), a gasotransmitter with protective effects in the cardiovascular system, is endogenously generated by three main enzymatic pathways: cystathionine gamma lyase (CTH), cystathionine beta synthase (CBS) and 3-mercaptopyruvate sulfurtransferase (MPST) enzymes. CTH and MPST are t...

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Detalles Bibliográficos
Autores principales:	Katsouda, Antonia, Markou, Maria, Zampas, Paraskevas, Varela, Aimilia, Davos, Constantinos H., Vellecco, Valentina, Cirino, Giuseppe, Bucci, Mariarosaria, Papapetropoulos, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969096/ https://www.ncbi.nlm.nih.gov/pubmed/36860295 http://dx.doi.org/10.3389/fphar.2023.1090654

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