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Efficacy and safety of a biomarker-driven cetuximab-based treatment regimen over 3 treatment lines in mCRC patients with RAS/BRAF wild type tumors at start of first line: The CAPRI 2 GOIM trial
BACKGROUND: Monoclonal antibodies targeting EGFR such as cetuximab or panitumumab represent a major step forward in the treatment of RAS wild type (WT) metastatic colorectal cancer (mCRC). Unfortunately, primary and acquired resistance mechanisms occur, with a huge percentage of patients succumbing...
Autores principales: | Martini, Giulia, Ciardiello, Davide, Napolitano, Stefania, Martinelli, Erika, Troiani, Teresa, Latiano, Tiziana Pia, Avallone, Antonio, Normanno, Nicola, Di Maio, Massimo, Maiello, Evaristo, Ciardiello, Fortunato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969187/ https://www.ncbi.nlm.nih.gov/pubmed/36860319 http://dx.doi.org/10.3389/fonc.2023.1069370 |
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