Discrimination between protein glycoforms using lectin-functionalised gold nanoparticles as signal enhancers

Glycoforms (and other post-translational modifications) of otherwise identical proteins can indicate pathogenesis/disease state and hence new tools to detect and sense a protein's glycosylation status are essential. Antibody-based assays against specific protein sequences do not typically discr...

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Detalles Bibliográficos
Autores principales: Neves, Marta M. P. S., Richards, Sarah-Jane, Baker, Alexander N., Walker, Marc, Georgiou, Panagiotis G., Gibson, Matthew I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969229/
https://www.ncbi.nlm.nih.gov/pubmed/36651292
http://dx.doi.org/10.1039/d2nh00470d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969229/
https://www.ncbi.nlm.nih.gov/pubmed/36651292
http://dx.doi.org/10.1039/d2nh00470d

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