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Discrimination between protein glycoforms using lectin-functionalised gold nanoparticles as signal enhancers
Glycoforms (and other post-translational modifications) of otherwise identical proteins can indicate pathogenesis/disease state and hence new tools to detect and sense a protein's glycosylation status are essential. Antibody-based assays against specific protein sequences do not typically discr...
Autores principales: | Neves, Marta M. P. S., Richards, Sarah-Jane, Baker, Alexander N., Walker, Marc, Georgiou, Panagiotis G., Gibson, Matthew I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969229/ https://www.ncbi.nlm.nih.gov/pubmed/36651292 http://dx.doi.org/10.1039/d2nh00470d |
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