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Prevention and control of chicken coccidiosis construction of recombinant Lactococcus lactis expressing chicken IL-4 and IL-2 fusion protein and its immune synergistic effect on chicken coccidia live vaccine

Intestinal mucosa injury and loss of weight gain are unavoidable while using live vaccine strain to prevent chicken coccidiosis. In this study, recombinant Lactococcus lactis NZ3900/pNZ8149-IL-4-IL-2, expressing the fusion protein of chicken IL-4 and IL-2, was constructed using food-grade NICE expre...

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Detalles Bibliográficos
Autores principales:	Zheng, Longlong, Zhang, Li, Tan, Fan, Wang, Chen, Lv, Xiaoling, Bai, Rui, Huo, Nairui, Zheng, Mingxue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Immunology, Health and Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969317/ https://www.ncbi.nlm.nih.gov/pubmed/36805402 http://dx.doi.org/10.1016/j.psj.2023.102530

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