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Antibodies Against Glutamic Acid Decarboxylase 65 Are Locally Produced in the CSF and Arise During Affinity Maturation

BACKGROUND AND OBJECTIVES: Antibodies (Abs) against the cytoplasmic protein glutamic acid decarboxylase 65 (GAD65) are detected in patients with neurologic syndromes together referred to as GAD65-Ab spectrum disorders. The response of some of these patients to plasma exchange or immunoglobulins indi...

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Detalles Bibliográficos
Autores principales:	Biljecki, Michelle, Eisenhut, Katharina, Beltrán, Eduardo, Winklmeier, Stephan, Mader, Simone, Thaller, Anna, Eichhorn, Peter, Steininger, Philipp, Flierl-Hecht, Andrea, Lewerenz, Jan, Kümpfel, Tania, Kerschensteiner, Martin, Meinl, Edgar, Thaler, Franziska S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969496/ https://www.ncbi.nlm.nih.gov/pubmed/36823135 http://dx.doi.org/10.1212/NXI.0000000000200090

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