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Integrative analysis of bulk and single-cell gene expression profiles to identify tumor-associated macrophage-derived CCL18 as a therapeutic target of esophageal squamous cell carcinoma

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is a common gastrointestinal malignancy with poor patient prognosis. Current treatment for ESCC, including immunotherapy, is only beneficial for a small subset of patients. Better characterization of the tumor microenvironment (TME) and the devel...

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Detalles Bibliográficos
Autores principales:	Sui, Xinghua, Chen, Chunxia, Zhou, Xiuman, Wen, Xueyan, Shi, Chao, Chen, Guanyu, Liu, Juan, He, Zhuoying, Yao, Yongjie, Li, Yin, Gao, Yanfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969639/ https://www.ncbi.nlm.nih.gov/pubmed/36850011 http://dx.doi.org/10.1186/s13046-023-02612-5

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