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Liver failure following biliopancreatic diversions: a narrative review: Falência hepática após derivações biliopancreáticas: uma revisão narrativa
CONTEXT AND OBJECTIVE: Occurrences of liver failure following jejunoileal bypass were extensively reported in the past and were one of the main factors that led to abandonment of this procedure. The newer predominantly malabsorptive procedures called biliopancreatic diversions (BPDs) have also been...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Paulista de Medicina - APM
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969727/ https://www.ncbi.nlm.nih.gov/pubmed/28380179 http://dx.doi.org/10.1590/1516-3180.2016.0129220616 |
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author | Cazzo, Everton Pareja, José Carlos Chaim, Elinton Adami |
author_facet | Cazzo, Everton Pareja, José Carlos Chaim, Elinton Adami |
author_sort | Cazzo, Everton |
collection | PubMed |
description | CONTEXT AND OBJECTIVE: Occurrences of liver failure following jejunoileal bypass were extensively reported in the past and were one of the main factors that led to abandonment of this procedure. The newer predominantly malabsorptive procedures called biliopancreatic diversions (BPDs) have also been implicated in several cases of acute and subacute liver failure. The aim here was to review the current available evidence on occurrences of liver failure following BPDs. DESIGN AND SETTING: Narrative review; bariatric surgery service of a public university hospital. METHODS: A review of the literature was conducted through an online search of medical databases. RESULTS: Associations between BPDs and liver failure have only infrequently been reported in the literature. However, they appear to be more than merely anecdotal. The pathophysiological mechanisms remain obscure, but they seem to be related to rapid weight loss, protein malnutrition, deficits of hepatotrophic factors, high circulating levels of free fatty acids and bacterial overgrowth in the bypassed bowel segments. Reversal of the BPD may ameliorate the liver impairment. CONCLUSIONS: Although infrequent, liver failure remains a concern following BPDs. Careful follow-up is required in individuals who undergo any BPD. |
format | Online Article Text |
id | pubmed-9969727 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Associação Paulista de Medicina - APM |
record_format | MEDLINE/PubMed |
spelling | pubmed-99697272023-02-28 Liver failure following biliopancreatic diversions: a narrative review: Falência hepática após derivações biliopancreáticas: uma revisão narrativa Cazzo, Everton Pareja, José Carlos Chaim, Elinton Adami Sao Paulo Med J Review Article CONTEXT AND OBJECTIVE: Occurrences of liver failure following jejunoileal bypass were extensively reported in the past and were one of the main factors that led to abandonment of this procedure. The newer predominantly malabsorptive procedures called biliopancreatic diversions (BPDs) have also been implicated in several cases of acute and subacute liver failure. The aim here was to review the current available evidence on occurrences of liver failure following BPDs. DESIGN AND SETTING: Narrative review; bariatric surgery service of a public university hospital. METHODS: A review of the literature was conducted through an online search of medical databases. RESULTS: Associations between BPDs and liver failure have only infrequently been reported in the literature. However, they appear to be more than merely anecdotal. The pathophysiological mechanisms remain obscure, but they seem to be related to rapid weight loss, protein malnutrition, deficits of hepatotrophic factors, high circulating levels of free fatty acids and bacterial overgrowth in the bypassed bowel segments. Reversal of the BPD may ameliorate the liver impairment. CONCLUSIONS: Although infrequent, liver failure remains a concern following BPDs. Careful follow-up is required in individuals who undergo any BPD. Associação Paulista de Medicina - APM 2016-11-10 /pmc/articles/PMC9969727/ /pubmed/28380179 http://dx.doi.org/10.1590/1516-3180.2016.0129220616 Text en © 2022 by Associação Paulista de Medicina https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons license. |
spellingShingle | Review Article Cazzo, Everton Pareja, José Carlos Chaim, Elinton Adami Liver failure following biliopancreatic diversions: a narrative review: Falência hepática após derivações biliopancreáticas: uma revisão narrativa |
title | Liver failure following biliopancreatic diversions: a narrative review: Falência hepática após derivações biliopancreáticas: uma revisão narrativa |
title_full | Liver failure following biliopancreatic diversions: a narrative review: Falência hepática após derivações biliopancreáticas: uma revisão narrativa |
title_fullStr | Liver failure following biliopancreatic diversions: a narrative review: Falência hepática após derivações biliopancreáticas: uma revisão narrativa |
title_full_unstemmed | Liver failure following biliopancreatic diversions: a narrative review: Falência hepática após derivações biliopancreáticas: uma revisão narrativa |
title_short | Liver failure following biliopancreatic diversions: a narrative review: Falência hepática após derivações biliopancreáticas: uma revisão narrativa |
title_sort | liver failure following biliopancreatic diversions: a narrative review: falência hepática após derivações biliopancreáticas: uma revisão narrativa |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969727/ https://www.ncbi.nlm.nih.gov/pubmed/28380179 http://dx.doi.org/10.1590/1516-3180.2016.0129220616 |
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