Linear IgA bullous dermatosis and elevated bullous interleukin‐6 levels: Responsive to treatment with Anti‐IL‐6 receptor monoclonals

Linear IgA bullous dermatosis (LABD) is  a rare autoimmune/inflammatory skin condition. Here, we report on a patient who developed treatment resistant LABD. At diagnosis, elevations of IL‐6 and C‐reactive protein in the blood and extreme elevations of IL‐6 in LABD bullous fluid were seen. The patien...

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Autores principales: Jordan, Stanley C., Balzer, Bonnie, Nast, Cynthia, Atienza, Janet, Lim, Katherine, Kumar, Sanjeev, Nissen, Nicholas, Shin, Bongha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969760/
https://www.ncbi.nlm.nih.gov/pubmed/36860726
http://dx.doi.org/10.1002/ccr3.6998
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author Jordan, Stanley C.
Balzer, Bonnie
Nast, Cynthia
Atienza, Janet
Lim, Katherine
Kumar, Sanjeev
Nissen, Nicholas
Shin, Bongha
author_facet Jordan, Stanley C.
Balzer, Bonnie
Nast, Cynthia
Atienza, Janet
Lim, Katherine
Kumar, Sanjeev
Nissen, Nicholas
Shin, Bongha
author_sort Jordan, Stanley C.
collection PubMed
description Linear IgA bullous dermatosis (LABD) is  a rare autoimmune/inflammatory skin condition. Here, we report on a patient who developed treatment resistant LABD. At diagnosis, elevations of IL‐6 and C‐reactive protein in the blood and extreme elevations of IL‐6 in LABD bullous fluid were seen. The patient responded well to tocilizumab (anti‐IL‐6 receptor) treatment.
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spelling pubmed-99697602023-02-28 Linear IgA bullous dermatosis and elevated bullous interleukin‐6 levels: Responsive to treatment with Anti‐IL‐6 receptor monoclonals Jordan, Stanley C. Balzer, Bonnie Nast, Cynthia Atienza, Janet Lim, Katherine Kumar, Sanjeev Nissen, Nicholas Shin, Bongha Clin Case Rep Case Report Linear IgA bullous dermatosis (LABD) is  a rare autoimmune/inflammatory skin condition. Here, we report on a patient who developed treatment resistant LABD. At diagnosis, elevations of IL‐6 and C‐reactive protein in the blood and extreme elevations of IL‐6 in LABD bullous fluid were seen. The patient responded well to tocilizumab (anti‐IL‐6 receptor) treatment. John Wiley and Sons Inc. 2023-02-27 /pmc/articles/PMC9969760/ /pubmed/36860726 http://dx.doi.org/10.1002/ccr3.6998 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Jordan, Stanley C.
Balzer, Bonnie
Nast, Cynthia
Atienza, Janet
Lim, Katherine
Kumar, Sanjeev
Nissen, Nicholas
Shin, Bongha
Linear IgA bullous dermatosis and elevated bullous interleukin‐6 levels: Responsive to treatment with Anti‐IL‐6 receptor monoclonals
title Linear IgA bullous dermatosis and elevated bullous interleukin‐6 levels: Responsive to treatment with Anti‐IL‐6 receptor monoclonals
title_full Linear IgA bullous dermatosis and elevated bullous interleukin‐6 levels: Responsive to treatment with Anti‐IL‐6 receptor monoclonals
title_fullStr Linear IgA bullous dermatosis and elevated bullous interleukin‐6 levels: Responsive to treatment with Anti‐IL‐6 receptor monoclonals
title_full_unstemmed Linear IgA bullous dermatosis and elevated bullous interleukin‐6 levels: Responsive to treatment with Anti‐IL‐6 receptor monoclonals
title_short Linear IgA bullous dermatosis and elevated bullous interleukin‐6 levels: Responsive to treatment with Anti‐IL‐6 receptor monoclonals
title_sort linear iga bullous dermatosis and elevated bullous interleukin‐6 levels: responsive to treatment with anti‐il‐6 receptor monoclonals
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969760/
https://www.ncbi.nlm.nih.gov/pubmed/36860726
http://dx.doi.org/10.1002/ccr3.6998
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