Cargando…

Nanocapillary sampling coupled to liquid chromatography mass spectrometry delivers single cell drug measurement and lipid fingerprints

This work describes the development of a new approach to measure drug levels and lipid fingerprints in single living mammalian cells. Nanocapillary sampling is an approach that enables the selection and isolation of single living cells under microscope observation. Here, live single cell nanocapilla...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lewis, Holly-May, Gupta, Priyanka, Saunders, Kyle D. G., Briones, Shazneil, von Gerichten, Johanna, Townsend, Paul A., Velliou, Eirini, Beste, Dany J. V., Cexus, Olivier, Webb, Roger, Bailey, Melanie J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9969958/ https://www.ncbi.nlm.nih.gov/pubmed/36723178 http://dx.doi.org/10.1039/d2an01732f

Ejemplares similares

Single-Cell Lipidomics Using Analytical Flow LC-MS Characterizes the Response to Chemotherapy in Cultured Pancreatic Cancer Cells
por: Saunders, Kyle D. G., et al.
Publicado: (2023)

Phase transitions of ordered ice in graphene nanocapillaries and carbon nanotubes
por: Raju, Muralikrishna, et al.
Publicado: (2018)

ERK and AKT phosphorylation status in lung cancer and emphysema using nanocapillary isoelectric focusing
por: Crosbie, Philip A J, et al.
Publicado: (2016)

High-Throughput Nanocapillary Filling Enabled by Microwave Radiation for Scanning Ion Conductance Microscopy Imaging
por: Navikas, Vytautas, et al.
Publicado: (2020)

Transmission of Hundred-keV Protons through Insulating Nanocapillaries: Charge-patch-assisted Specular Reflections
por: Wang, G. Y., et al.
Publicado: (2015)

Quantitative Analysis and Fingerprint Profiles for Quality Control of Fructus Schisandrae by Gas Chromatography: Mass Spectrometry
por: Xia, Yong-Gang, et al.
Publicado: (2014)

Identification of metabolic fingerprints in severe obstructive sleep apnea using gas chromatography–Mass spectrometry
por: Mohit,, et al.
Publicado: (2022)

Gas Chromatography-Ion Mobility Spectrometry Detection of Odor Fingerprint as Markers of Rapeseed Oil Refined Grade
por: Chen, Tong, et al.
Publicado: (2019)

Volatile Fingerprint of Italian Populations of Orchids Using Solid Phase Microextraction and Gas Chromatography Coupled with Mass Spectrometry
por: Manzo, Alessandra, et al.
Publicado: (2014)

Color discrimination and gas chromatography-mass spectrometry fingerprint based on chemometrics analysis for the quality evaluation of Schizonepetae Spica
por: Liu, Xindan, et al.
Publicado: (2020)

Distinguishing between Contact and Administration of Heroin from a Single Fingerprint using High Resolution Mass Spectrometry
por: Costa, Catia, et al.
Publicado: (2019)

Metabolic fingerprinting of chemotherapy-resistant prostate cancer stem cells. An untargeted metabolomic approach by liquid chromatography-mass spectrometry
por: Bort, Alicia, et al.
Publicado: (2022)

The Development of a Three-Dimensional Platform for Patient-Derived Ovarian Cancer Tissue Models: A Systematic Literature Review
por: Sevinyan, Lusine, et al.
Publicado: (2022)

Untargeted saliva metabolomics by liquid chromatography—Mass spectrometry reveals markers of COVID-19 severity
por: Frampas, Cecile F., et al.
Publicado: (2022)

Quantitation of cyclic nucleotides in mammalian cells and in human urine by high-performance liquid chromatography/mass spectrometry
por: Burhenne, Heike, et al.
Publicado: (2011)

3d tissue models as tools for radiotherapy screening for pancreatic cancer
por: Wishart, Gabrielle, et al.
Publicado: (2021)

On the Evaluation of a Novel Hypoxic 3D Pancreatic Cancer Model as a Tool for Radiotherapy Treatment Screening
por: Wishart, Gabrielle, et al.
Publicado: (2021)

Novel Anticancer and Treatment Sensitizing Compounds against Pancreatic Cancer
por: Wishart, Gabrielle, et al.
Publicado: (2021)

Current strategies with implementation of three-dimensional cell culture: the challenge of quantification
por: Temple, Jonathan, et al.
Publicado: (2022)

Enhanced effect of X-rays in the presence of a static magnetic field within a 3D pancreatic cancer model
por: Wishart, Gabrielle, et al.
Publicado: (2023)

Chemical Fingerprint and Metabolic Profile Analysis of Tianshu Tablets by Ultra-High Performance Liquid Chromatography/Quadrupole-Time of Flight Mass Spectrometry
por: Chen, Lin, et al.
Publicado: (2019)

Serum metabolic fingerprinting of psoriasis and psoriatic arthritis patients using solid-phase microextraction—liquid chromatography—high-resolution mass spectrometry
por: Looby, Nikita, et al.
Publicado: (2021)

Analytical Strategies for Fingerprinting of Antioxidants, Nutritional Substances, and Bioactive Compounds in Foodstuffs Based on High Performance Liquid Chromatography–Mass Spectrometry: An Overview
por: Donno, Dario, et al.
Publicado: (2020)

Fingerprint analysis of Resina Draconis by ultra-performance liquid chromatography
por: Xue, Yudi, et al.
Publicado: (2017)

A Systematic Comparative Assessment of the Response of Ovarian Cancer Cells to the Chemotherapeutic Cisplatin in 3D Models of Various Structural and Biochemical Configurations—Does One Model Type Fit All?
por: Gupta, Priyanka, et al.
Publicado: (2022)

Comparative Analysis and Development of a Flavor Fingerprint for Volatile Compounds of Vegetable Soybean Seeds Based on Headspace-Gas Chromatography-Ion Mobility Spectrometry
por: Yuan, Fengjie, et al.
Publicado: (2021)

Comparative Analysis of Volatile Constituents in Root Tuber and Rhizome of Curcuma longa L. Using Fingerprints and Chemometrics Approaches on Gas Chromatography–Mass Spectrometry
por: Tang, Guang-Mei, et al.
Publicado: (2022)

Analysis of Volatile Compounds and Flavor Fingerprint Using Gas Chromatography–Ion Mobility Spectrometry ( GC-IMS) on Crassostrea gigas with Different Ploidy and Gender
por: Fu, Jingjing, et al.
Publicado: (2023)

Meta-Analysis of COVID-19 Metabolomics Identifies Variations in Robustness of Biomarkers
por: Onoja, Anthony, et al.
Publicado: (2023)

Scopes of Bioanalytical Chromatography–Mass Spectrometry
por: Savelieva, E. I.
Publicado: (2021)

Chemoradiotherapy screening in a novel biomimetic polymer based pancreatic cancer model
por: Gupta, Priyanka, et al.
Publicado: (2019)

Gas chromatography and mass spectrometry : a practical guide
por: Kitson, Fulton G.
Publicado: (1996)

Gas chromatography and mass spectrometry : a practical guide /
por: Sparkman, O. David (Orrin David), 1942-
Publicado: (2011)

Fingerprint analysis of placenta polypeptide injection by high performance liquid chromatography
por: Huang, Li, et al.
Publicado: (2012)

Fingerprints of volatile flavor compounds from southern stinky tofu brine with headspace solid‐phase microextraction/gas chromatography–mass spectrometry and chemometric methods
por: Li, Pao, et al.
Publicado: (2019)

Simultaneous quantification of amiloride and hydrochlorothiazide in human plasma by liquid chromatography–tandem mass spectrometry
por: Shah, Jaivik V., et al.
Publicado: (2017)

Immediate early gene fingerprints of multi-component behaviour
por: Rook, Noemi, et al.
Publicado: (2020)

Quantitation by Portable Gas Chromatography: Mass Spectrometry of VOCs Associated with Vapor Intrusion
por: Fair, Justin D., et al.
Publicado: (2010)

Use of headspace–gas chromatography–ion mobility spectrometry to detect volatile fingerprints of palm fibre oil and sludge palm oil in samples of crude palm oil
por: Othman, Abrizah, et al.
Publicado: (2019)

Back to the Basics of Liquid Chromatography-Mass Spectrometry
por: Kim, Young Jin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2lfsn8cse7d0ekqd3c05khotrq