IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood. Our aim was to evaluate serum IL‐31 as a putative biomarker of pruritus in clinical trials of an farnesoid X receptor (FXR) agonist, cilofexor, in patients wit...

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Detalles Bibliográficos
Autores principales: Xu, Jun, Wang, Ya, Khoshdeli, Mina, Peach, Matt, Chuang, Jen‐Chieh, Lin, Julie, Tsai, Wen‐Wei, Mahadevan, Sangeetha, Minto, Wesley, Diehl, Lauri, Gupta, Ruchi, Trauner, Michael, Patel, Keyur, Noureddin, Mazen, Kowdley, Kris V., Gulamhusein, Aliya, Bowlus, Christopher L., Huss, Ryan S., Myers, Robert P., Chung, Chuhan, Billin, Andrew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Articles: Immune-Mediated Diseases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970017/
https://www.ncbi.nlm.nih.gov/pubmed/35686937
http://dx.doi.org/10.1002/hep.32599

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