Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its efficacy remains limited. To identify immunotherapy‐susceptible HCC, we profiled the molecular abnormalities and tumor immune microenvironment (TIME) of rapidly increasing nonviral HCC. APPROACHES AND...

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Detalles Bibliográficos
Autores principales: Murai, Hiroki, Kodama, Takahiro, Maesaka, Kazuki, Tange, Shoichiro, Motooka, Daisuke, Suzuki, Yutaka, Shigematsu, Yasuyuki, Inamura, Kentaro, Mise, Yoshihiro, Saiura, Akio, Ono, Yoshihiro, Takahashi, Yu, Kawasaki, Yota, Iino, Satoshi, Kobayashi, Shogo, Idogawa, Masashi, Tokino, Takashi, Hashidate‐Yoshida, Tomomi, Shindou, Hideo, Miyazaki, Masanori, Imai, Yasuharu, Tanaka, Satoshi, Mita, Eiji, Ohkawa, Kazuyoshi, Hikita, Hayato, Sakamori, Ryotaro, Tatsumi, Tomohide, Eguchi, Hidetoshi, Morii, Eiichi, Takehara, Tetsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Articles: Liver Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970024/
https://www.ncbi.nlm.nih.gov/pubmed/35567547
http://dx.doi.org/10.1002/hep.32573

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