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Paclitaxel effects on axonal localization and vesicular trafficking of Na(V)1.8
Patients treated with paclitaxel (PTX) or other antineoplastic agents can experience chemotherapy-induced peripheral neuropathy (CIPN), a debilitating side effect characterized by numbness and pain. PTX interferes with microtubule-based transport, which inhibits tumor growth via cell cycle arrest bu...
Autores principales: | Baker, Christopher A., Tyagi, Sidharth, Higerd-Rusli, Grant P., Liu, Shujun, Zhao, Peng, Dib-Hajj, Fadia B., Waxman, Stephen G., Dib-Hajj, Sulayman D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970094/ https://www.ncbi.nlm.nih.gov/pubmed/36860665 http://dx.doi.org/10.3389/fnmol.2023.1130123 |
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