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Paclitaxel effects on axonal localization and vesicular trafficking of Na(V)1.8

Patients treated with paclitaxel (PTX) or other antineoplastic agents can experience chemotherapy-induced peripheral neuropathy (CIPN), a debilitating side effect characterized by numbness and pain. PTX interferes with microtubule-based transport, which inhibits tumor growth via cell cycle arrest bu...

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Detalles Bibliográficos
Autores principales: Baker, Christopher A., Tyagi, Sidharth, Higerd-Rusli, Grant P., Liu, Shujun, Zhao, Peng, Dib-Hajj, Fadia B., Waxman, Stephen G., Dib-Hajj, Sulayman D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970094/
https://www.ncbi.nlm.nih.gov/pubmed/36860665
http://dx.doi.org/10.3389/fnmol.2023.1130123

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