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Syncope With Sinus Arrest Following a Single Dose of a COVID-19 Vaccine

Vaccines against the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) are of paramount importance in combating the current coronavirus disease 2019 (COVID-19) pandemic. Syncopal episodes following routine vaccinations are well-reported; however, only a few cases of syncope following SARS-...

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Detalles Bibliográficos
Autores principales: Ghoweba, Mohamed, Sabayon, Muhie Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970110/
https://www.ncbi.nlm.nih.gov/pubmed/36860236
http://dx.doi.org/10.7759/cureus.34309
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author Ghoweba, Mohamed
Sabayon, Muhie Dean
author_facet Ghoweba, Mohamed
Sabayon, Muhie Dean
author_sort Ghoweba, Mohamed
collection PubMed
description Vaccines against the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) are of paramount importance in combating the current coronavirus disease 2019 (COVID-19) pandemic. Syncopal episodes following routine vaccinations are well-reported; however, only a few cases of syncope following SARS-CoV-2 vaccines exist in the literature. This is a case report of a 21-year-old female patient who developed recurrent syncopal attacks over three months that started one day after receiving the first dose of the Pfizer-BioNTech COVID-19 vaccine (Pfizer, New York City; BioNTech, Mainz, Germany). Holter monitoring during successive episodes showed progressive bradycardia followed by a prolonged sinus arrest. The patient eventually required pacemaker placement that resulted in the total resolution of her symptoms. Further studies are required to investigate a possible correlation and the mechanisms involved.
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spelling pubmed-99701102023-02-28 Syncope With Sinus Arrest Following a Single Dose of a COVID-19 Vaccine Ghoweba, Mohamed Sabayon, Muhie Dean Cureus Cardiology Vaccines against the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) are of paramount importance in combating the current coronavirus disease 2019 (COVID-19) pandemic. Syncopal episodes following routine vaccinations are well-reported; however, only a few cases of syncope following SARS-CoV-2 vaccines exist in the literature. This is a case report of a 21-year-old female patient who developed recurrent syncopal attacks over three months that started one day after receiving the first dose of the Pfizer-BioNTech COVID-19 vaccine (Pfizer, New York City; BioNTech, Mainz, Germany). Holter monitoring during successive episodes showed progressive bradycardia followed by a prolonged sinus arrest. The patient eventually required pacemaker placement that resulted in the total resolution of her symptoms. Further studies are required to investigate a possible correlation and the mechanisms involved. Cureus 2023-01-28 /pmc/articles/PMC9970110/ /pubmed/36860236 http://dx.doi.org/10.7759/cureus.34309 Text en Copyright © 2023, Ghoweba et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Ghoweba, Mohamed
Sabayon, Muhie Dean
Syncope With Sinus Arrest Following a Single Dose of a COVID-19 Vaccine
title Syncope With Sinus Arrest Following a Single Dose of a COVID-19 Vaccine
title_full Syncope With Sinus Arrest Following a Single Dose of a COVID-19 Vaccine
title_fullStr Syncope With Sinus Arrest Following a Single Dose of a COVID-19 Vaccine
title_full_unstemmed Syncope With Sinus Arrest Following a Single Dose of a COVID-19 Vaccine
title_short Syncope With Sinus Arrest Following a Single Dose of a COVID-19 Vaccine
title_sort syncope with sinus arrest following a single dose of a covid-19 vaccine
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970110/
https://www.ncbi.nlm.nih.gov/pubmed/36860236
http://dx.doi.org/10.7759/cureus.34309
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