Characterization of Novel Derivatives of MBQ-167, an Inhibitor of the GTP-binding Proteins Rac/Cdc42

Rac and Cdc42, are homologous GTPases that regulate cell migration, invasion, and cell-cycle progression; thus, representing key targets for metastasis therapy. We previously reported on the efficacy of MBQ-167, which blocks both Rac1 and Cdc42 in breast cancer cells and mouse models of metastasis....

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Detalles Bibliográficos
Autores principales: Medina, Julia I., Cruz-Collazo, Ailed, Maldonado, Maria del Mar, Matos Gascot, Tatiana, Borrero-Garcia, Luis D., Cooke, Mariana, Kazanietz, Marcelo G., Hernandez O'Farril, Eliud, Vlaar, Cornelis P., Dharmawardhane, Suranganie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970268/
https://www.ncbi.nlm.nih.gov/pubmed/36861094
http://dx.doi.org/10.1158/2767-9764.CRC-22-0303

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