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Aortic Root Surgery in Adults: An Unsolved Problem

Nowadays, despite the rapid advancements in interventional cardiology, open surgery still deals with aortic root diseases, to assure the best “ad hoc” treatment. In case of middle-aged adult patients, the optimal operation still represents a matter of debate. A review of the last 10-year literature...

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Autores principales: Brega, Carlotta, Albertini, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers, Inc. 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970757/
https://www.ncbi.nlm.nih.gov/pubmed/36848909
http://dx.doi.org/10.1055/s-0042-1757949
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author Brega, Carlotta
Albertini, Alberto
author_facet Brega, Carlotta
Albertini, Alberto
author_sort Brega, Carlotta
collection PubMed
description Nowadays, despite the rapid advancements in interventional cardiology, open surgery still deals with aortic root diseases, to assure the best “ad hoc” treatment. In case of middle-aged adult patients, the optimal operation still represents a matter of debate. A review of the last 10-year literature was conducted, focusing on patients below 65 to 70 years of age. Because of the small sample and the heterogeneity of the papers, no metanalysis was possible. Bentall–de Bono procedure, valve sparing, and Ross operations are the surgical options currently available. The main issues in the Bentall – de Bono operation are lifelong anticoagulation therapy and cavitation in case of mechanical prosthesis implantation and structural valve degeneration in case of biological Bentall. As transcatheter procedures are currently performed as valve in valve, biological prosthesis may be preferable, if the diameter may prevent postoperative high gradients. Conservative techniques, such as remodeling and reimplantation, preferred in the young, guarantee physiologic aortic root dynamics and impose surgical analysis of the aortic root structures to get a durable result. The Ross operation, which shows excellent performance, involves autologous pulmonary valve implantation and is performed only in experienced and high-volume centers. Due to its technical difficulty, it requires a steep learning curve and presents some limitations in specific aortic valve diseases. All three have advantages and downsides, and no ideal solution has still been reported.
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spelling pubmed-99707572023-02-28 Aortic Root Surgery in Adults: An Unsolved Problem Brega, Carlotta Albertini, Alberto Aorta (Stamford) Nowadays, despite the rapid advancements in interventional cardiology, open surgery still deals with aortic root diseases, to assure the best “ad hoc” treatment. In case of middle-aged adult patients, the optimal operation still represents a matter of debate. A review of the last 10-year literature was conducted, focusing on patients below 65 to 70 years of age. Because of the small sample and the heterogeneity of the papers, no metanalysis was possible. Bentall–de Bono procedure, valve sparing, and Ross operations are the surgical options currently available. The main issues in the Bentall – de Bono operation are lifelong anticoagulation therapy and cavitation in case of mechanical prosthesis implantation and structural valve degeneration in case of biological Bentall. As transcatheter procedures are currently performed as valve in valve, biological prosthesis may be preferable, if the diameter may prevent postoperative high gradients. Conservative techniques, such as remodeling and reimplantation, preferred in the young, guarantee physiologic aortic root dynamics and impose surgical analysis of the aortic root structures to get a durable result. The Ross operation, which shows excellent performance, involves autologous pulmonary valve implantation and is performed only in experienced and high-volume centers. Due to its technical difficulty, it requires a steep learning curve and presents some limitations in specific aortic valve diseases. All three have advantages and downsides, and no ideal solution has still been reported. Thieme Medical Publishers, Inc. 2023-02-27 /pmc/articles/PMC9970757/ /pubmed/36848909 http://dx.doi.org/10.1055/s-0042-1757949 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Brega, Carlotta
Albertini, Alberto
Aortic Root Surgery in Adults: An Unsolved Problem
title Aortic Root Surgery in Adults: An Unsolved Problem
title_full Aortic Root Surgery in Adults: An Unsolved Problem
title_fullStr Aortic Root Surgery in Adults: An Unsolved Problem
title_full_unstemmed Aortic Root Surgery in Adults: An Unsolved Problem
title_short Aortic Root Surgery in Adults: An Unsolved Problem
title_sort aortic root surgery in adults: an unsolved problem
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970757/
https://www.ncbi.nlm.nih.gov/pubmed/36848909
http://dx.doi.org/10.1055/s-0042-1757949
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