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Lung and Cerebral Nocardiosis Caused by Nocardia elegans in a Lung Transplant Recipient: A Case Report and Literature Review

Patients after lung transplantation are at risk for Nocardia infections. We herein report a case of lung and cerebral nocardiosis caused by Nocardia elegans, a rare species of Nocardia, in a lung transplant recipient. Antibiotic therapy, including sulfamethoxazole-trimethoprim (ST), and brain absces...

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Autores principales: Omori, Keitaro, Kitagawa, Hiroki, Nagaoka, Rie, Naka, Yasuhiko, Kawamoto, Kazuma, Horimasu, Yasushi, Nomura, Toshihito, Shigemoto, Norifumi, Yaguchi, Takashi, Hattori, Noboru, Ohge, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970818/
https://www.ncbi.nlm.nih.gov/pubmed/35831116
http://dx.doi.org/10.2169/internalmedicine.9813-22
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author Omori, Keitaro
Kitagawa, Hiroki
Nagaoka, Rie
Naka, Yasuhiko
Kawamoto, Kazuma
Horimasu, Yasushi
Nomura, Toshihito
Shigemoto, Norifumi
Yaguchi, Takashi
Hattori, Noboru
Ohge, Hiroki
author_facet Omori, Keitaro
Kitagawa, Hiroki
Nagaoka, Rie
Naka, Yasuhiko
Kawamoto, Kazuma
Horimasu, Yasushi
Nomura, Toshihito
Shigemoto, Norifumi
Yaguchi, Takashi
Hattori, Noboru
Ohge, Hiroki
author_sort Omori, Keitaro
collection PubMed
description Patients after lung transplantation are at risk for Nocardia infections. We herein report a case of lung and cerebral nocardiosis caused by Nocardia elegans, a rare species of Nocardia, in a lung transplant recipient. Antibiotic therapy, including sulfamethoxazole-trimethoprim (ST), and brain abscess drainage improved symptoms and imaging findings. A literature review of N. elegans infections showed that 12 of 14 cases (85.7%) were reported from East Asia, particularly Japan (9 cases, 64.2%). The lungs were the predominant site (12/14 cases, 85.7%), and most of the cases were susceptible to ST (9/10 cases, 90%).
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spelling pubmed-99708182023-02-28 Lung and Cerebral Nocardiosis Caused by Nocardia elegans in a Lung Transplant Recipient: A Case Report and Literature Review Omori, Keitaro Kitagawa, Hiroki Nagaoka, Rie Naka, Yasuhiko Kawamoto, Kazuma Horimasu, Yasushi Nomura, Toshihito Shigemoto, Norifumi Yaguchi, Takashi Hattori, Noboru Ohge, Hiroki Intern Med Case Report Patients after lung transplantation are at risk for Nocardia infections. We herein report a case of lung and cerebral nocardiosis caused by Nocardia elegans, a rare species of Nocardia, in a lung transplant recipient. Antibiotic therapy, including sulfamethoxazole-trimethoprim (ST), and brain abscess drainage improved symptoms and imaging findings. A literature review of N. elegans infections showed that 12 of 14 cases (85.7%) were reported from East Asia, particularly Japan (9 cases, 64.2%). The lungs were the predominant site (12/14 cases, 85.7%), and most of the cases were susceptible to ST (9/10 cases, 90%). The Japanese Society of Internal Medicine 2022-07-14 2023-02-01 /pmc/articles/PMC9970818/ /pubmed/35831116 http://dx.doi.org/10.2169/internalmedicine.9813-22 Text en Copyright © 2023 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Omori, Keitaro
Kitagawa, Hiroki
Nagaoka, Rie
Naka, Yasuhiko
Kawamoto, Kazuma
Horimasu, Yasushi
Nomura, Toshihito
Shigemoto, Norifumi
Yaguchi, Takashi
Hattori, Noboru
Ohge, Hiroki
Lung and Cerebral Nocardiosis Caused by Nocardia elegans in a Lung Transplant Recipient: A Case Report and Literature Review
title Lung and Cerebral Nocardiosis Caused by Nocardia elegans in a Lung Transplant Recipient: A Case Report and Literature Review
title_full Lung and Cerebral Nocardiosis Caused by Nocardia elegans in a Lung Transplant Recipient: A Case Report and Literature Review
title_fullStr Lung and Cerebral Nocardiosis Caused by Nocardia elegans in a Lung Transplant Recipient: A Case Report and Literature Review
title_full_unstemmed Lung and Cerebral Nocardiosis Caused by Nocardia elegans in a Lung Transplant Recipient: A Case Report and Literature Review
title_short Lung and Cerebral Nocardiosis Caused by Nocardia elegans in a Lung Transplant Recipient: A Case Report and Literature Review
title_sort lung and cerebral nocardiosis caused by nocardia elegans in a lung transplant recipient: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970818/
https://www.ncbi.nlm.nih.gov/pubmed/35831116
http://dx.doi.org/10.2169/internalmedicine.9813-22
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