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Increased PRL-1 in BM-derived MSCs triggers anaerobic metabolism via mitochondria in a cholestatic rat model

Mesenchymal stem cell (MSC) therapy in chronic liver disease is associated with mitochondrial anaerobic metabolism. Phosphatase of regenerating liver-1 (PRL-1), known as protein tyrosine phosphatase type 4A, member 1 (PTP4A1), plays a critical role in liver regeneration. However, its therapeutic mec...

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Detalles Bibliográficos
Autores principales: Kim, Jae Yeon, Kim, Se Ho, Seok, Jin, Bae, Si Hyun, Hwang, Seong-Gyu, Kim, Gi Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970868/
https://www.ncbi.nlm.nih.gov/pubmed/36865088
http://dx.doi.org/10.1016/j.omtn.2023.01.017