Cargando…

Effects and Potential Mechanism of Zhuyu Pill Against Atherosclerosis: Network Pharmacology and Experimental Validation

BACKGROUND: Atherosclerosis (AS) is an immunoinflammatory disease associated with dyslipidemia. Zhuyu Pill (ZYP) is a classic Chinese herbal compound that has been shown to exhibit anti-inflammatory and lipid-lowering effects on AS in our previous studies. However, the underlying mechanisms by which...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pan, Yingying, Feng, Xianrong, Song, Wei, Zhou, Xin, Zhou, Zhen, Chen, Gaoyang, Shen, Tao, Zhang, Xiaobo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970883/ https://www.ncbi.nlm.nih.gov/pubmed/36866196 http://dx.doi.org/10.2147/DDDT.S398808

Ejemplares similares

Mechanism of interventional effect and targets of Zhuyu pill in regulating and suppressing colitis and cholestasis
por: Yu, Han, et al.
Publicado: (2022)

Network pharmacological analysis of Xuefu Zhuyu decoction in the treatment of atherosclerosis
por: Yuan, Jinxia, et al.
Publicado: (2022)

Zhuyu Pill Alleviates Nonalcoholic Fatty Liver Disease by Regulating Bile Acid Metabolism through the Gut–Liver Axis
por: Xu, Lu, et al.
Publicado: (2023)

Efficacy of Zhuyu Pill Intervention in a Cholestasis Rat Model: Mutual Effects on Fecal Metabolism and Microbial Diversity
por: Yu, Han, et al.
Publicado: (2021)

Potential active compounds and molecular mechanism of Xuefu Zhuyu decoction for atherosclerosis, based on network pharmacology and molecular docking
por: Li, Yingyun, et al.
Publicado: (2022)

Effect of Xuefu Zhuyu Capsule on Myocardial Infarction: Network Pharmacology and Experimental Verification
por: Duan, Jinlong, et al.
Publicado: (2023)

Exploring the Pharmacological Mechanisms of Xihuang Pills Against Prostate Cancer via Integrating Network Pharmacology and Experimental Validation In Vitro and In Vivo
por: Wu, Yongrong, et al.
Publicado: (2022)

The zhuyu pill relieves rat cholestasis by regulating the mRNA expression of lipid and bile metabolism associated genes
por: Han, Jun, et al.
Publicado: (2023)

Systematic Pharmacology and GEO Database Mining Revealed the Therapeutic Mechanism of Xuefu Zhuyu Decoration for Atherosclerosis Cardiovascular Disease
por: Liang, Bin, et al.
Publicado: (2020)

Analysis of the Anti-Tumour Effect of Xuefu Zhuyu Decoction Based on Network Pharmacology and Experimental Verification in Drosophila
por: Wang, Sitong, et al.
Publicado: (2022)

Exploring Pharmacological Mechanisms of Xuefu Zhuyu Decoction in the Treatment of Traumatic Brain Injury via a Network Pharmacology Approach
por: Zhong, Yuanyuan, et al.
Publicado: (2018)

Research on Effect and Mechanism of Xuefu Zhuyu Decoction on CHD Based on Meta-Analysis and Network Pharmacology
por: Kui, Fuguang, et al.
Publicado: (2021)

Xuefu zhuyu decoction improves cognitive impairment in experimental traumatic brain injury via synaptic regulation
por: Zhou, Jing, et al.
Publicado: (2017)

Uncovering the Pharmacological Mechanisms of Gexia-Zhuyu Formula (GXZY) in Treating Liver Cirrhosis by an Integrative Pharmacology Strategy
por: Cao, Xu, et al.
Publicado: (2022)

XuefuZhuyu decoction protected cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy
por: Shi, Xiaowen, et al.
Publicado: (2017)

Exploring potential mechanisms of Suhexiang Pill against COVID-19 based on network pharmacology and molecular docking
por: Li, Jialin, et al.
Publicado: (2021)

Qihuang Zhuyu Formula Attenuates Atherosclerosis via Targeting PPARγ to Regulate Cholesterol Efflux and Endothelial Cell Inflammation
por: Wang, Mengxi, et al.
Publicado: (2022)

Potential Mechanisms of Biejiajian Pill in the Treatment of Diabetic Atherosclerosis Based on Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation
por: Zhu, Rong, et al.
Publicado: (2022)

Mechanism investigation of Duhuo Jisheng pill against rheumatoid arthritis based on a strategy for the integration of network pharmacology, molecular docking and in vivo experimental verification
por: Xin, Ping, et al.
Publicado: (2023)

Analysis of the Clinical Efficacy and Molecular Mechanism of Xuefu Zhuyu Decoction in the Treatment of COPD Based on Meta-Analysis and Network Pharmacology
por: Hu, Yu, et al.
Publicado: (2022)

Metabolomics Deciphers Potential Targets of Xuefu Zhuyu Decoction Against Traumatic Brain Injury in Rat
por: Li, Teng, et al.
Publicado: (2020)

Network pharmacology and experimental validation to elucidate the pharmacological mechanisms of Bushen Huashi decoction against kidney stones
por: Liu, Haizhao, et al.
Publicado: (2023)

Mechanism of Tao Hong Decoction in the treatment of atherosclerosis based on network pharmacology and experimental validation
por: Li, SiJin, et al.
Publicado: (2023)

Pharmacological Mechanism of Ganlu Powder in the Treatment of NASH Based on Network Pharmacology and Molecular Docking
por: Gao, Rui, et al.
Publicado: (2022)

Network pharmacology-based strategy to investigate pharmacological mechanism of Liuwei Dihuang Pill against postmenopausal osteoporosis
por: Wang, Qingchan, et al.
Publicado: (2022)

Mechanisms of resveratrol against diabetic wound by network pharmacology and experimental validation
por: Youjun, Ding, et al.
Publicado: (2023)

Shaofu Zhuyu Decoction Regresses Endometriotic Lesions in a Rat Model
por: Zhu, Guanghui, et al.
Publicado: (2018)

Study on the Mechanism of Improving HIV/AIDS Immune Function with Jian Aikang Concentrated Pill Based on Network Pharmacology Combined with Experimental Validation
por: Shao, Cancan, et al.
Publicado: (2022)

Clinical antitumor application and pharmacological mechanisms of Dahuang Zhechong Pill
por: Tian, Yingying, et al.
Publicado: (2023)

Integration of Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanisms of Zhuanggu Busui Formula Against Osteoporosis
por: Zhang, Huihao, et al.
Publicado: (2022)

Mechanism of Liuwei Dihuang Pills in treating osteoporosis based on network pharmacology
por: Wang, Xiqoqiang, et al.
Publicado: (2023)

Effect of Xuefu Zhuyu Decoction Pretreatment on Myocardium in Sepsis Rats
por: Meng, Fansu, et al.
Publicado: (2018)

Integrating Network Pharmacology and Experimental Validation to Decipher the Mechanism of Action of Huanglian Jiedu Decoction in Treating Atherosclerosis
por: Liang, Jiahua, et al.
Publicado: (2021)

The mechanism by which Naru 3 pill protects against intervertebral disc cartilage endplate degeneration based on network pharmacology and experimental verification
por: Guo, Jialin, et al.
Publicado: (2023)

Mechanisms of dihydromyricetin against hepatocellular carcinoma elucidated by network pharmacology combined with experimental validation
por: Zhang, Shuo, et al.
Publicado: (2023)

An Integrated Gut Microbiota and Network Pharmacology Study on Fuzi-Lizhong Pill for Treating Diarrhea-Predominant Irritable Bowel Syndrome
por: Zhen, Zhang, et al.
Publicado: (2021)

Molecular Mechanisms of Luteolin Against Atopic Dermatitis Based on Network Pharmacology and in vivo Experimental Validation
por: Tang, Liu, et al.
Publicado: (2022)

Analysis of the potential biological mechanisms of Danyu Gukang Pill against osteonecrosis of the femoral head based on network pharmacology
por: Guo, Yongchang, et al.
Publicado: (2023)

Network pharmacology-based analysis in determining the mechanisms of Huoxin pill in protecting against myocardial infarction
por: He, Jia, et al.
Publicado: (2021)

Exploring the potential mechanisms of Shiwei Hezi pill against nephritis based on the method of network pharmacology
por: Wei, Lei
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8u92po0b9ckj1181dpta33i70i