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Side-by-Side Comparison of uPAR-Targeting Optical Imaging Antibodies and Antibody Fragments for Fluorescence-Guided Surgery of Solid Tumors
PURPOSE: Radical resection is paramount for curative oncological surgery. Fluorescence-guided surgery (FGS) aids in intraoperative identification of tumor-positive resection margins. This study aims to assess the feasibility of urokinase plasminogen activator receptor (uPAR) targeting antibody fragm...
Autores principales: | Baart, Victor M., van Manen, Labrinus, Bhairosingh, Shadhvi S., Vuijk, Floris A., Iamele, Luisa, de Jonge, Hugo, Scotti, Claudia, Resnati, Massimo, Cordfunke, Robert A., Kuppen, Peter J. K., Mazar, Andrew P., Burggraaf, Jacobus, Vahrmeijer, Alexander L., Sier, Cornelis F. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970952/ https://www.ncbi.nlm.nih.gov/pubmed/34642899 http://dx.doi.org/10.1007/s11307-021-01657-2 |
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