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Investigation of TLR4 Antagonists for Prevention of Intestinal Inflammation
Activation of toll-like receptor 4 (TLR4) has been shown to be a major influence on the inflammatory signalling pathways in intestinal mucositis (IM), as demonstrated by TLR4 knock-out mice. Pharmacological TLR4 inhibition has thus been postulated as a potential new therapeutic approach for the trea...
Autores principales: | Tam, Janine S. Y., Coller, Janet K., Prestidge, Clive A., Bowen, Joanne M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971050/ https://www.ncbi.nlm.nih.gov/pubmed/35867263 http://dx.doi.org/10.1007/s10753-022-01714-0 |
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