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The Evolution of Fluorescence-Guided Surgery

There has been continual development of fluorescent agents, imaging systems, and their applications over the past several decades. With the recent FDA approvals of 5-aminolevulinic acid, hexaminolevulinate, and pafolacianine, much of the potential that fluorescence offers for image-guided oncologic...

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Autores principales: Van Keulen, Stan, Hom, Marisa, White, Haley, Rosenthal, Eben L., Baik, Fred M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971137/
https://www.ncbi.nlm.nih.gov/pubmed/36123445
http://dx.doi.org/10.1007/s11307-022-01772-8
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author Van Keulen, Stan
Hom, Marisa
White, Haley
Rosenthal, Eben L.
Baik, Fred M
author_facet Van Keulen, Stan
Hom, Marisa
White, Haley
Rosenthal, Eben L.
Baik, Fred M
author_sort Van Keulen, Stan
collection PubMed
description There has been continual development of fluorescent agents, imaging systems, and their applications over the past several decades. With the recent FDA approvals of 5-aminolevulinic acid, hexaminolevulinate, and pafolacianine, much of the potential that fluorescence offers for image-guided oncologic surgery is now being actualized. In this article, we review the evolution of fluorescence-guided surgery, highlight the milestones which have contributed to successful clinical translation, and examine the future of targeted fluorescence imaging.
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spelling pubmed-99711372023-03-01 The Evolution of Fluorescence-Guided Surgery Van Keulen, Stan Hom, Marisa White, Haley Rosenthal, Eben L. Baik, Fred M Mol Imaging Biol Review Article There has been continual development of fluorescent agents, imaging systems, and their applications over the past several decades. With the recent FDA approvals of 5-aminolevulinic acid, hexaminolevulinate, and pafolacianine, much of the potential that fluorescence offers for image-guided oncologic surgery is now being actualized. In this article, we review the evolution of fluorescence-guided surgery, highlight the milestones which have contributed to successful clinical translation, and examine the future of targeted fluorescence imaging. Springer International Publishing 2022-09-19 2023 /pmc/articles/PMC9971137/ /pubmed/36123445 http://dx.doi.org/10.1007/s11307-022-01772-8 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Article
Van Keulen, Stan
Hom, Marisa
White, Haley
Rosenthal, Eben L.
Baik, Fred M
The Evolution of Fluorescence-Guided Surgery
title The Evolution of Fluorescence-Guided Surgery
title_full The Evolution of Fluorescence-Guided Surgery
title_fullStr The Evolution of Fluorescence-Guided Surgery
title_full_unstemmed The Evolution of Fluorescence-Guided Surgery
title_short The Evolution of Fluorescence-Guided Surgery
title_sort evolution of fluorescence-guided surgery
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971137/
https://www.ncbi.nlm.nih.gov/pubmed/36123445
http://dx.doi.org/10.1007/s11307-022-01772-8
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