Cargando…
Noncanonical electromechanical coupling paths in cardiac hERG potassium channel
Voltage-gated potassium channels are involved in many physiological processes such as nerve impulse transmission, the heartbeat, and muscle contraction. However, for many of them the molecular determinants of the gating mechanism remain elusive. Here, using a combination of theoretical and experimen...
Autores principales: | Bassetto, Carlos A. Z., Costa, Flavio, Guardiani, Carlo, Bezanilla, Francisco, Giacomello, Alberto |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971164/ https://www.ncbi.nlm.nih.gov/pubmed/36849440 http://dx.doi.org/10.1038/s41467-023-36730-7 |
Ejemplares similares
-
Molecular dynamics simulations suggest possible activation and deactivation pathways in the hERG channel
por: Costa, Flavio, et al.
Publicado: (2022) -
Integrated Approach
Including Docking, MD Simulations,
and Network Analysis Highlights the Action Mechanism of the Cardiac
hERG Activator RPR260243
por: Costa, Flavio, et al.
Publicado: (2023) -
Na(+) Permeation and Block of hERG Potassium Channels
por: Gang, Hongying, et al.
Publicado: (2006) -
Stereoselective Inhibition of the hERG1 Potassium Channel
por: Grilo, Liliana Sintra, et al.
Publicado: (2010) -
Voltage-Dependent Gating of hERG Potassium Channels
por: Cheng, Yen May, et al.
Publicado: (2012)