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Subtype-selective induction of apoptosis in translocation-related sarcoma cells induced by PUMA and BIM upon treatment with pan-PI3K inhibitors

Translocation-related sarcomas (TRSs) harbor an oncogenic fusion gene generated by chromosome translocation and account for approximately one-third of all sarcomas; however, effective targeted therapies have yet to be established. We previously reported that a pan-phosphatidylinositol 3-kinase (PI3K...

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Detalles Bibliográficos
Autores principales:	Isoyama, Sho, Tamaki, Naomi, Noguchi, Yutaka, Okamura, Mutsumi, Yoshimatsu, Yuki, Kondo, Tadashi, Suzuki, Takeshi, Yaguchi, Shin-ichi, Dan, Shingo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971170/ https://www.ncbi.nlm.nih.gov/pubmed/36849535 http://dx.doi.org/10.1038/s41419-023-05690-7

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