Cargando…
Analgesic effects of a highly selective mPGES-1 inhibitor
The growing opioid use and overdose crisis in the US is closely related to the abuse of pain medications. Particularly for postoperative pain (POP), ~ 310 million major surgeries are performed globally per year. Most patients undergoing surgical procedures experience acute POP, and ~ 75% of those wi...
Autores principales: | Stewart, Madeline J., Weaver, Lauren M., Ding, Kai, Kyomuhangi, Annet, Loftin, Charles D., Zheng, Fang, Zhan, Chang-Guo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971260/ https://www.ncbi.nlm.nih.gov/pubmed/36849491 http://dx.doi.org/10.1038/s41598-023-30164-3 |
Ejemplares similares
-
DREAM-in-CDM Approach and Identification of a New Generation of Anti-inflammatory Drugs Targeting mPGES-1
por: Zhou, Shuo, et al.
Publicado: (2020) -
Structure-based discovery of mPGES-1 inhibitors suitable for preclinical testing in wild-type mice as a new generation of anti-inflammatory drugs
por: Ding, Kai, et al.
Publicado: (2018) -
Arzanol, a Potent mPGES-1 Inhibitor: Novel Anti-Inflammatory Agent
por: Kothavade, Pankaj S., et al.
Publicado: (2013) -
Targeting mPGES-1 as a New Strategy against Neuroblastoma
por: Comunanza, Valentina
Publicado: (2018) -
Simultaneous expression of COX-2 and mPGES-1 in mouse gastrointestinal hamartomas
por: Takeda, H, et al.
Publicado: (2004)