In patients with hemophilia, a decreased thrombin generation profile is associated with a severe bleeding phenotype

BACKGROUND: Heterogeneity in clinical bleeding phenotype has been observed in hemophilia patients with similar FVIII or FIX activity levels. Thrombin generation and plasmin generation, as a global hemostasis assay, may contribute to a better prediction of which patients are at an increased risk of b...

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Detalles Bibliográficos
Autores principales: Verhagen, Marieke J.A., van Heerde, Waander L., van der Bom, Johanna G., Beckers, Erik A.M., Blijlevens, Nicole M.A., Coppens, Michiel, Gouw, Samantha C., Jansen, Joop H., Leebeek, Frank W.G., van Vulpen, Lize F.D., Meijer, Daniëlle, Schols, Saskia E.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971314/
https://www.ncbi.nlm.nih.gov/pubmed/36865907
http://dx.doi.org/10.1016/j.rpth.2023.100062

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