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Yeast display platform with expression of linear peptide epitopes for high-throughput assessment of peptide-MHC-II binding

Yeast display can serve as a powerful tool to assess the binding of peptides to the major histocompatibility complex (pMHC) and pMHC-T-cell receptor binding. However, this approach is often limited by the need to optimize MHC proteins for yeast surface expression, which can be laborious and may not...

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Detalles Bibliográficos
Autores principales: Huisman, Brooke D., Balivada, Pallavi A., Birnbaum, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971316/
https://www.ncbi.nlm.nih.gov/pubmed/36649909
http://dx.doi.org/10.1016/j.jbc.2023.102913