DNA repair protein FANCD2 has both ubiquitination-dependent and ubiquitination-independent functions during germ cell development

When DNA interstrand crosslink lesions occur, a core complex of Fanconi anemia proteins promotes the ubiquitination of FANCD2 and FANCI, which recruit downstream factors to repair the lesion. However, FANCD2 maintains genome stability not only through its ubiquitination-dependent but also its ubiqui...

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Detalles Bibliográficos
Autores principales: Zhao, Simin, Huang, Chengzi, Yang, Yajuan, Xu, Weiwei, Yu, Yongze, Wen, Canxin, Cao, Lili, Gao, Fei, Qin, Yingying, Chen, Zi-Jiang, Guo, Ting, Zhao, Shidou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971320/
https://www.ncbi.nlm.nih.gov/pubmed/36642183
http://dx.doi.org/10.1016/j.jbc.2023.102905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971320/
https://www.ncbi.nlm.nih.gov/pubmed/36642183
http://dx.doi.org/10.1016/j.jbc.2023.102905

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