H3K27me3 Demethylases Maintain the Transcriptional and Epigenomic Landscape of the Intestinal Epithelium

BACKGROUND & AIMS: Although trimethylation of histone H3 lysine 27 (H3K27me3) by polycomb repressive complex 2 is required for intestinal function, the role of the antagonistic process—H3K27me3 demethylation—in the intestine remains unknown. The aim of this study was to determine the contributio...

Descripción completa

Detalles Bibliográficos
Autores principales: Kolev, Hannah M., Swisa, Avital, Manduchi, Elisabetta, Lan, Yemin, Stine, Rachel R., Testa, Giuseppe, Kaestner, Klaus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971508/
https://www.ncbi.nlm.nih.gov/pubmed/36503150
http://dx.doi.org/10.1016/j.jcmgh.2022.12.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971508/
https://www.ncbi.nlm.nih.gov/pubmed/36503150
http://dx.doi.org/10.1016/j.jcmgh.2022.12.001

Ejemplares similares