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H3K27me3 Demethylases Maintain the Transcriptional and Epigenomic Landscape of the Intestinal Epithelium

BACKGROUND & AIMS: Although trimethylation of histone H3 lysine 27 (H3K27me3) by polycomb repressive complex 2 is required for intestinal function, the role of the antagonistic process—H3K27me3 demethylation—in the intestine remains unknown. The aim of this study was to determine the contributio...

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Detalles Bibliográficos
Autores principales:	Kolev, Hannah M., Swisa, Avital, Manduchi, Elisabetta, Lan, Yemin, Stine, Rachel R., Testa, Giuseppe, Kaestner, Klaus H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971508/ https://www.ncbi.nlm.nih.gov/pubmed/36503150 http://dx.doi.org/10.1016/j.jcmgh.2022.12.001

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