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UHRF1-induced connexin26 methylation is involved in hearing damage triggered by intermittent hypoxia in neonatal rats

Ubiquitin-like with plant homeodomain and ring finger domains 1 (UHRF1) promotes the maintenance of established patterns of DNA methylation in mammalian cells. Extensive methylation of connexin26 (COX26) during hearing impairment has been demonstrated. The present study aims to determine whether UHR...

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Detalles Bibliográficos
Autores principales: Zhang, Xingang, Zheng, Jishan, Xu, Huiqing, Ma, Zhaoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971736/
https://www.ncbi.nlm.nih.gov/pubmed/36865496
http://dx.doi.org/10.1515/med-2023-0650