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The MRN complex and topoisomerase IIIa–RMI1/2 synchronize DNA resection motor proteins

DNA resection—the nucleolytic processing of broken DNA ends—is the first step of homologous recombination. Resection is catalyzed by the resectosome, a multienzyme complex that includes bloom syndrome helicase (BLM), DNA2 or exonuclease 1 nucleases, and additional DNA-binding proteins. Although the...

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Detalles Bibliográficos
Autores principales:	Soniat, Michael M., Nguyen, Giaochau, Kuo, Hung-Che, Finkelstein, Ilya J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9971906/ https://www.ncbi.nlm.nih.gov/pubmed/36529288 http://dx.doi.org/10.1016/j.jbc.2022.102802

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