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Association between a single nucleotide polymorphism in the R3HCC1 gene and irinotecan toxicity

OBJECTIVE: Irinotecan is a useful anticancer drug for colorectal cancer treatment. UGT1A1*28 and *6 gene polymorphisms are known risk factors for irinotecan‐associated toxicity. However, severe adverse effects due to irinotecan have been observed even in patients who do not harbor UGT1A1*28 or *6. W...

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Detalles Bibliográficos
Autores principales:	Kanesada, Kou, Tsunedomi, Ryouichi, Hazama, Shoichi, Ogihara, Hiroyuki, Hamamoto, Yoshihiko, Shindo, Yoshitaro, Matsui, Hiroto, Tokumitsu, Yukio, Yoshida, Shin, Iida, Michihisa, Suzuki, Nobuaki, Takeda, Shigeru, Ioka, Tatsuya, Nagano, Hiroaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	RESEARCH ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972014/ https://www.ncbi.nlm.nih.gov/pubmed/36308049 http://dx.doi.org/10.1002/cam4.5299

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