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Drug library screening identifies histone deacetylase inhibition as a novel therapeutic strategy for choriocarcinoma

BACKGROUND: Choriocarcinoma is a rare and aggressive gynecological malignancy. The standard treatment is systemic chemotherapy as choriocarcinoma exhibits high chemosensitivity. However, refractory choriocarcinoma exhibits chemoresistance; thus, the prognosis remains very poor. This study aimed to i...

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Detalles Bibliográficos
Autores principales: Watanabe, Eri, Yokoi, Akira, Yoshida, Kosuke, Sugiyama, Mai, Kitagawa, Masami, Nishino, Kimihiro, Yamamoto, Eiko, Niimi, Kaoru, Yamamoto, Yusuke, Kajiyama, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972027/
https://www.ncbi.nlm.nih.gov/pubmed/36106577
http://dx.doi.org/10.1002/cam4.5243