Cargando…

Oral application of magnesium‐L‐threonate enhances analgesia and reduces the dosage of opioids needed in advanced cancer patients—A randomized, double‐blind, placebo‐controlled trial

PURPOSE: To investigate the effects of oral administration of magnesium‐L‐threonate, a novel magnesium compound, on the analgesic effect of opioids in patients with advanced cancer. METHODS: We performed a prospective, randomized, double‐blind trial at a tertiary hospital in Shanghai, China. Eligibl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Siyin, Jin, Tian, Ma, Bingjie, Ji, Yun, Huang, Xuehua, Wang, Peiliang, Liu, Xiaoming, Krylov, Boris V., Liu, Xianguo, Ma, Ke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	RESEARCH ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972038/ https://www.ncbi.nlm.nih.gov/pubmed/36703238 http://dx.doi.org/10.1002/cam4.4922

Ejemplares similares

Neuroprotective effects of magnesium l-threonate in a hypoxic zebrafish model
por: Kim, Young-Sung, et al.
Publicado: (2020)

A Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Therapeutic Effect of Magnesium-L-Threonate Supplementation for Persistent Pain After Breast Cancer Surgery
por: Ni, Yuncheng, et al.
Publicado: (2023)

Effects of Vitamin C and Magnesium L-threonate Treatment on Learning and Memory in Lead-poisoned Mice
por: Bislimi, Kemajl, et al.
Publicado: (2021)

A Magtein(®), Magnesium L-Threonate, -Based Formula Improves Brain Cognitive Functions in Healthy Chinese Adults
por: Zhang, Chengxiang, et al.
Publicado: (2022)

Treatment Of Magnesium-L-Threonate Elevates The Magnesium Level In The Cerebrospinal Fluid And Attenuates Motor Deficits And Dopamine Neuron Loss In A Mouse Model Of Parkinson’s disease
por: Shen, Yanling, et al.
Publicado: (2019)

Magnesium-L-threonate exhibited a neuroprotective effect against oxidative stress damage in HT22 cells and Alzheimer’s disease mouse model
por: Xiong, Ying, et al.
Publicado: (2022)

Development and Evaluation of Novel Metformin Derivative Metformin Threonate for Brain Ischemia Treatment
por: Zhang, Gufang, et al.
Publicado: (2022)

Micronized Organic Magnesium Salts Enhance Opioid Analgesia in Rats
por: Bujalska-Zadrożny, Magdalena, et al.
Publicado: (2016)

Patient-Controlled Intravenous Analgesia with or without Ultrasound-Guided Bilateral Intercostal Nerve Blocks in Children Undergoing the Nuss Procedure: A Randomized, Double-Blinded, Controlled Trial
por: Ma, Bingjie, et al.
Publicado: (2022)

Experience with opioids does not modify the brain network involved in expectations of placebo analgesia
por: Wicht, Corentin A., et al.
Publicado: (2022)

Savor the flavor: A randomized double‐blind study assessing taste‐enhanced placebo analgesia in healthy volunteers
por: Zunhammer, Matthias, et al.
Publicado: (2022)

Placebo Analgesia, Acupuncture and Sham Surgery
por: Liu, Tao, et al.
Publicado: (2011)

Effects of Magnesium Citrate, Magnesium Oxide, and Magnesium Sulfate Supplementation on Arterial Stiffness: A Randomized, Double‐Blind, Placebo‐Controlled Intervention Trial
por: Schutten, Joëlle C., et al.
Publicado: (2022)

Pharmacogenomic considerations in opioid analgesia
por: Vuilleumier, Pascal H, et al.
Publicado: (2012)

Effect of magnesium infusion on thoracic epidural analgesia
por: Gupta, Sampa Dutta, et al.
Publicado: (2011)

Translocator protein agonist Ro5-4864 alleviates neuropathic pain and promotes remyelination in the sciatic nerve
por: Ma, Bingjie, et al.
Publicado: (2017)

Effect of wound infiltration with bupivacaine or lower dose bupivacaine/magnesium versus placebo for postoperative analgesia after cesarean section
por: Eldaba, Ahmad A., et al.
Publicado: (2013)

Central inhibition and placebo analgesia
por: Zhuo, Min
Publicado: (2005)

Age-Stratified Propofol Dosage for Pediatric Procedural Sedation and Analgesia
por: van Dijk, Huib, et al.
Publicado: (2023)

Opioid Analgesia and Opioid-Induced Adverse Effects: A Review
por: Paul, Alok K., et al.
Publicado: (2021)

Comparison of Bupivacaine Plus Magnesium Sulfate and Ropivacaine Plus Magnesium Sulfate Infiltration for Postoperative Analgesia in Patients Undergoing Lumbar Laminectomy: A Randomized Double-blinded Study
por: Hazarika, Rajib, et al.
Publicado: (2017)

Preoperative dexamethasone for acute post-thoracotomy analgesia: a randomized, double-blind, placebo-controlled study
por: Joung, Kyoung-Woon, et al.
Publicado: (2018)

The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial
por: Abbasi, Behnood, et al.
Publicado: (2012)

Effects of Preoperative Magnesium Sulphate on Post-Cesarean Pain, A Placebo Controlled Double Blind Study
por: Mireskandari, Seyed Mohamad, et al.
Publicado: (2015)

A Randomized Double-blind Placebo-controlled Trial on the Effect of Magnesium Oxide in Patients With Chronic Constipation
por: Mori, Sumire, et al.
Publicado: (2019)

Intravenous magnesium sulfate for postoperative analgesia after abdominal hysterectomy under spinal anesthesia: a randomized, double-blind trial
por: Benevides, Márcio Luiz, et al.
Publicado: (2021)

Effects of magnesium sulfate on periarticular infiltration analgesia in total knee arthroplasty: a prospective, double-blind, randomized controlled trial
por: Zhao, Chengcheng, et al.
Publicado: (2023)

Magnesium Sulfate and Sufentanil for Patient-Controlled Analgesia in Orthopedic Surgery
por: Sedighinejad, Abass, et al.
Publicado: (2014)

The effect of magnesium sulphate on postoperative analgesia requirements in gynecological surgeries
por: Asadollah, Sara, et al.
Publicado: (2015)

Epidural and opioid analgesia following the Nuss procedure
por: Walaszczyk, Malgorzata, et al.
Publicado: (2011)

Did gender affect opioids for analgesia and anesthesia?
por: Chen, Nanjin, et al.
Publicado: (2022)

Time-dependent analysis of dosage delivery information for patient-controlled analgesia services
por: Kuo, I-Ting, et al.
Publicado: (2018)

Genetic Polymorphisms of Cytokines Might Affect Postoperative Sufentanil Dosage for Analgesia in Patients
por: Guo, Jian, et al.
Publicado: (2020)

Intraoperative Remifentanil Dosage in Surgery for Adolescent Idiopathic Scoliosis Does Not Increase Postoperative Opioid Consumption When Combined With Epidural Analgesia: A Retrospective Cohort Study
por: Aoki, Yoshitaka, et al.
Publicado: (2021)

S-ketamine in patient-controlled analgesia reduces opioid consumption in a dose-dependent manner after major lumbar fusion surgery: A randomized, double-blind, placebo-controlled clinical trial
por: Brinck, Elina C. V., et al.
Publicado: (2021)

High-volume infiltration analgesia in bilateral hip arthroplasty: A randomized, double-blind placebo-controlled trial
por: Andersen, Lasse Ø, et al.
Publicado: (2011)

Low-dose ketamine infusion for labor analgesia: A double-blind, randomized, placebo controlled clinical trial
por: Joel, Sam, et al.
Publicado: (2014)

Efficacy of postoperative analgesia with duloxetine in posthemorrhoidectomy pain: a prospective, randomized, double-blind and placebo-controlled trial
por: Gerber, Marlus Tavares, et al.
Publicado: (2022)

Comparing Clinical Efficacy of Non-Opioid and Opioid-Based Analgesia Protocols [Letter]
por: Li, Cheng-Wen, et al.
Publicado: (2023)

Somatotopy of placebo analgesia is independent of spatial attention
por: Domnick, Claudia, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_76fn3ivb966tngb7ru7m3pvgst