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Phase I study of plitidepsin in combination with bortezomib and dexamethasone in patients with relapsed/refractory multiple myeloma
Previous studies showed antitumor activity for plitidepsin plus dexamethasone (DXM) in relapsed/refractory multiple myeloma (r/r MM), and in vitro synergism with bortezomib (BTZ) or DXM against MM cells. This phase I trial evaluated plitidepsin (3‐h intravenous infusion Day 1 and 15), BTZ (subcutane...
Autores principales: | Mateos, María Victoria, Prosper, Felipe, Martin Sánchez, Jesús, Ocio, Enrique M., Oriol, Albert, Motlló, Cristina, Michot, Jean‐Marie, Jarque, Isidro, Iglesias, Rebeca, Solé, María, Martínez, Sara, Kahatt, Carmen, Fudio, Salvador, Corral, Gema, Zeaiter, Ali, Montilla, Lola, Ribrag, Vincent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972151/ https://www.ncbi.nlm.nih.gov/pubmed/36127823 http://dx.doi.org/10.1002/cam4.5250 |
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