Studies on the role of non-coding RNAs in controlling the activity of T cells in asthma

Bronchial asthma, commonly known as asthma, is a chronic inflammatory disease characterized by airway inflammation, increased responsiveness and changes in airway structure. T cells, particularly T helper cells, play a crucial role in the disease. Non-coding RNAs, which are RNAs that do not code for...

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Detalles Bibliográficos
Autores principales: Sufianov, Albert, Bessonova, Marina, Begliarzade, Sema, Kudriashov, Valentin, Danilov, Andrei, Ilyasova, Tatiana, Yaolou, Wang, Nafikova, Radmila, Beylerli, Ozal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972402/
https://www.ncbi.nlm.nih.gov/pubmed/36865391
http://dx.doi.org/10.1016/j.ncrna.2023.02.004
Descripción
Sumario:Bronchial asthma, commonly known as asthma, is a chronic inflammatory disease characterized by airway inflammation, increased responsiveness and changes in airway structure. T cells, particularly T helper cells, play a crucial role in the disease. Non-coding RNAs, which are RNAs that do not code for proteins, mainly include microRNAs, long non-coding RNAs, and circular RNAs, play a role in regulating various biological processes. Studies have shown that non-coding RNAs have an important role in the activation and transformation of T cells and other biological processes in asthma. The specific mechanisms and clinical applications are worth further examination. This article reviews the recent research on the role of microRNAs, long non-coding RNAs and circular RNAs in T cells in asthma.

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