Identification and Functional Characterization of Fungal Chalcone Synthase and Chalcone Isomerase

[Image: see text] By mining fungal genomic information, a noncanonical iterative type I PKS fused with an N-terminal adenylation–thiolation didomain, which catalyzes the formation of naringenin chalcone, was found. Structural prediction and molecular docking analysis indicated that a C-terminal thio...

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Detalles Bibliográficos
Autores principales: Furumura, Sho, Ozaki, Taro, Sugawara, Akihiro, Morishita, Yohei, Tsukada, Kento, Ikuta, Tatsuya, Inoue, Asuka, Asai, Teigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972472/
https://www.ncbi.nlm.nih.gov/pubmed/36762727
http://dx.doi.org/10.1021/acs.jnatprod.2c01027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972472/
https://www.ncbi.nlm.nih.gov/pubmed/36762727
http://dx.doi.org/10.1021/acs.jnatprod.2c01027

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