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Shared and unique effects of ApoEε4 and pathogenic gene mutation on cognition and imaging in preclinical familial Alzheimer’s disease

BACKGROUND: Neuropsychology and imaging changes have been reported in the preclinical stage of familial Alzheimer’s disease (FAD). This study investigated the effects of APOEε4 and known pathogenic gene mutation on different cognitive domains and circuit imaging markers in preclinical FAD. METHODS:...

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Detalles Bibliográficos
Autores principales: Quan, Meina, Wang, Qi, Qin, Wei, Wang, Wei, Li, Fangyu, Zhao, Tan, Li, Tingting, Qiu, Qiongqiong, Cao, Shuman, Wang, Shiyuan, Wang, Yan, Jin, Hongmei, Zhou, Aihong, Fang, Jiliang, Jia, Longfei, Jia, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972804/
https://www.ncbi.nlm.nih.gov/pubmed/36850008
http://dx.doi.org/10.1186/s13195-023-01192-y

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