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Total synthesis of the natural (−)-205B alkaloid and its activity toward α7 nAChRs
A new approach to the synthesis of the (−)-205B alkaloid is described in this paper. This work is characterised by the development of an efficient chirality transfer through a silyl tethered intramolecular alkylation reaction, an unprecedented tandem highly selective iridium catalyzed partial reduct...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972826/ https://www.ncbi.nlm.nih.gov/pubmed/36601968 http://dx.doi.org/10.1039/d2ob01723g |