Suppressor Mutations in LptF Bypass Essentiality of LptC by Forming a Six-Protein Transenvelope Bridge That Efficiently Transports Lipopolysaccharide

Lipopolysaccharide (LPS) is an essential component of the outer membrane (OM) of many Gram-negative bacteria, providing a barrier against the entry of toxic molecules. In Escherichia coli, LPS is exported to the cell surface by seven essential proteins (LptA-G) that form a transenvelope complex. At...

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Detalles Bibliográficos
Autores principales: Falchi, Federica A., Taylor, Rebecca J., Rowe, Sebastian J., Moura, Elisabete C. C. M., Baeta, Tiago, Laguri, Cedric, Simorre, Jean-Pierre, Kahne, Daniel E., Polissi, Alessandra, Sperandeo, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9972910/
https://www.ncbi.nlm.nih.gov/pubmed/36541759
http://dx.doi.org/10.1128/mbio.02202-22

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