Avian Influenza A Virus Polymerase Can Utilize Human ANP32 Proteins To Support cRNA but Not vRNA Synthesis

Host restriction limits the emergence of novel pandemic strains from the influenza A virus avian reservoir. For efficient replication in mammalian cells, the avian influenza RNA-dependent RNA polymerase must adapt to use human orthologues of the host factor ANP32, which lack a 33-amino-acid insertio...

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Detalles Bibliográficos
Autores principales: Swann, Olivia C., Rasmussen, Amalie B., Peacock, Thomas P., Sheppard, Carol M., Barclay, Wendy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973007/
https://www.ncbi.nlm.nih.gov/pubmed/36645303
http://dx.doi.org/10.1128/mbio.03399-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973007/
https://www.ncbi.nlm.nih.gov/pubmed/36645303
http://dx.doi.org/10.1128/mbio.03399-22

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