SARS-CoV-2 Uses Nonstructural Protein 16 To Evade Restriction by IFIT1 and IFIT3

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Understanding the molecular basis of innate immune evasion by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important consideration for designing the next wave of therapeutics. Here, we investigate the role of the nonstructural protein 16 (NSP16) of SARS-CoV-2 in infection and p...

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Detalles Bibliográficos
Autores principales: Schindewolf, Craig, Lokugamage, Kumari, Vu, Michelle N., Johnson, Bryan A., Scharton, Dionna, Plante, Jessica A., Kalveram, Birte, Crocquet-Valdes, Patricia A., Sotcheff, Stephanea, Jaworski, Elizabeth, Alvarado, Rojelio E., Debbink, Kari, Daugherty, Matthew D., Weaver, Scott C., Routh, Andrew L., Walker, David H., Plante, Kenneth S., Menachery, Vineet D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Cellular Response to Infection
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973020/
https://www.ncbi.nlm.nih.gov/pubmed/36722972
http://dx.doi.org/10.1128/jvi.01532-22
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