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A Virus-Packageable CRISPR System Identifies Host Dependency Factors Co-Opted by Multiple HIV-1 Strains

At each stage of the HIV life cycle, host cellular proteins are hijacked by the virus to establish and enhance infection. We adapted the virus packageable HIV-CRISPR screening technology at a genome-wide scale to comprehensively identify host factors that affect HIV replication in a human T cell lin...

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Detalles Bibliográficos
Autores principales: Montoya, Vanessa R., Ready, Trine M., Felton, Abby, Fine, Sydney R., OhAinle, Molly, Emerman, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973025/
https://www.ncbi.nlm.nih.gov/pubmed/36744886
http://dx.doi.org/10.1128/mbio.00009-23