A MAPS Vaccine Induces Multipronged Systemic and Tissue-Resident Cellular Responses and Protects Mice against Mycobacterium tuberculosis

Tuberculosis (TB) remains a leading cause of morbidity and mortality worldwide. To date, the mainstay of vaccination involves the use of Mycobacterium bovis bacillus Calmette-Guérin (BCG), a live-attenuated vaccine that confers protection against extrapulmonary disease in infants and children but no...

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Detalles Bibliográficos
Autores principales: O’Hara, Joanne M., Wakabayashi, Shoko, Siddiqi, Noman, Cheung, Elaine, Babunovic, Gregory H., Thompson, Claudette M., Lu, Ying-Jie, Rubin, Eric J., Malley, Richard, Zhang, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973048/
https://www.ncbi.nlm.nih.gov/pubmed/36749098
http://dx.doi.org/10.1128/mbio.03611-22

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