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Small-Molecule Inhibitor of Flaviviral NS3-NS5 Interaction with Broad-Spectrum Activity and Efficacy In Vivo

Every year, dengue virus (DENV) causes one hundred million infections worldwide that can result in dengue disease and severe dengue. Two other mosquito-borne flaviviruses, i.e., Zika virus (ZIKV) and West Nile virus (WNV), are responsible of prolonged outbreaks and are associated with severe neurolo...

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Detalles Bibliográficos
Autores principales:	Celegato, Marta, Sturlese, Mattia, Vasconcelos Costa, Vivian, Trevisan, Marta, Lallo Dias, Angélica Samer, Souza Passos, Ingredy Beatriz, Queiroz-Junior, Celso Martins, Messa, Lorenzo, Favaro, Annagiulia, Moro, Stefano, Teixeira, Mauro Martins, Loregian, Arianna, Mercorelli, Beatrice
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9973282/ https://www.ncbi.nlm.nih.gov/pubmed/36622141 http://dx.doi.org/10.1128/mbio.03097-22

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